Category: Nagpur Local

Nagpur:- It is important to get sufficient knowledge about the virus to win the battle against Covid-19’s global pandemic. To this end, the Council of Scientific and Industrial Research (CSIR) has initiated an ‘SEQ-Mission’ aimed at sequencing over 500 viral genomes from Covid.

Covid-19 is caused by a coronavirus, whose genetic material is RNA (ribonucleic acid), and not DNA. The virus is pathogenic according to scientists as it has some commands in its RNA that allow it to bind to humans.

Through using the sequencing method, it is possible to read the commands on a genome which is the entire gene set of a living organism. The SEQ-Mission method was compiled by Atya Kapley, senior lead scientist at the National Environmental Engineering Research Institute (Neeri), which is a constituent CSIR laboratory.

The compilation notes that genome sequencing will include the virus’ blueprint and help in the creation of improved clinical care systems. “The SEQ-Mission will concentrate on sequencing the viral genome from samples obtained from every part of the world. Through the number of samples, the better the interpretation of pathogenesis would be, “he said.

Kapley has told us that the country has already sequenced 28 Covid virus genomes. “CSIR plans to do 500 in four weeks’ time. There are samples of viruses from different positive patients. And if we do pan India we will see more clearly what kind of strains we are being contaminated with, “she added.

The additional said the sequencing would be carried out in-house at CSIR-IGIB (Delhi) and CSIR-CCMB (Hyderabad). Both institutes claim to have the sequencing facilities needed.

Highlighting the need to research more samples to battle the disease, the compilation said, “Much like the human genome project where it was important to sequence all races and populations recognize the similarity in our DNA as well as the specific characteristics of each race, in the case of Covid the same is important. It will help scientists understand why certain people are more vulnerable to different diseases, why some are safe, and so on.

Similarly, we need to sequence the virus through various regions of the world in order to understand variants, otherwise, we won’t be able to develop foolproof drugs and recognize how the virus is binding on human receptors. “The compilation added that mutations were found to be widespread in the SARS-CoV-2 genome (the coronavirus that caused Covid-19), adding that their protein expression is related to wi Mutations are variants of the original series.

“These clinical results are important to explain the many outbreaks that have occurred in various populations. There are three major recognized lineages for beta-corona virus (Lineages A-B-C), and lineage-B belongs to SARS-CoV-2. Such results have been possible from numerous tests, and are still being studied in many patients for respiratory infection, gastrointestinal, and CNS infection. It is therefore advisable to include several sequences and samples as India is second in the population of the world, “he said.

Highlighting the major advantages of sequencing the viral genome, Kapley said, “The most important consequence of the sequencing exercise is that it would reveal the genetic codes for viral pathogenesis and its lifecycle, its variants and binding patterns for drugs. All of these are important questions that need answers if we are to fight and conquer this pandemic.

Nagpur:- All satranjipura contact tested positive at the wanadongri quarantine center as per the sources late saturday night, reports of 17 people. For this 19 people tested positive in city on saturday.

With the latest growth, it has been told that the cases of the virus-borne disease are at 126 in the state’s second capital. The silver lining, however, is that 22 patients were successfully diagnosed with the disease and returned home.

Satranjipura’s cluttered region in nagpur continues to hit headlines with maximum corona patients coming from this hotspot. Both the district administration and the police are on their toes to tackle the crisis but the relief appears to be a far-fetched hope as every other day adds to the positive cases coming from the locality of satranjipura.

Nagpur: The number of positive patients from Satranjipura increased to 59 with seven more from city testing positive for Covid-19 on Friday. At the same time, the number of cases in seven days from one Mominpura family swelled to 11.

In the district, the total number of cases rose to 105. The number in town climbed to 101. One of seven new positive patients is from Satranjipura and reportedly a 68-year-old deceased neighbor, Covid-19’s first and only death in area. A woman, she has been under institutional quarantine since April 22 and was admitted to IGGMCH after positive testing.

Just the case of Satranjipura contributed 56.19% of the total incidents. Reports of the first and second samples of more than 140 individuals are still awaited. The samples of 150 people quarantined at MLA Hostel and Wanadongri were taken Friday. Also awaited are the accounts of these, all the deceased’s neighbours. Remaining six successful cases are from Mominpura taking a total of 24 that is 22.85% of the district’s total cases.

NMC Mahal-Gandhibagh Zone Zonal Medical Officer Dr Khwaja Moinuddin said, “Five people are 42-year-old immediate family members who had tested positive on April 18. Two are his brothers, one brother’s wife, and her 5-year-old child. The fifth person is his father’s brother,’ he said. Five family members of the person — father, mother, wife, and two children on April 21 had tested positive. And the cumulative number of positive people from this family now is 11.

The NMC team led by Khwaja had quarantined 27 persons from the family residing in one building at Chudi Gully, Mominpura, immediately after the individual was tested positive on April 18. Remaining reports are awaited.

NMC has begun tracking similar connections of 11 successful individuals. The 42-year-old was taking care of 8 Tablighi Jamaatis food and other requirements. Reporting of one more person (male, 38) from Mominpura came positive in late growth. The person’s information could not be identified via the NMC.

Mominpura Family * The 42-year-old resident of Chuddi Gully, Mominpura, tested positive on April 18 * He was caring for eight Jamaatis campsites in Darul Falah, Takia Deewanshah, Mominpura, Jabalpur.

* His five family members — father, mother, wife and two children tested positively on April 21

* Tests from his two parents, the wife of one of four parents, his child and his father’s brother were positive on Friday

* Tests from the remaining 16 family members are anticipated

* NMC is now monitoring near connections between all these individuals.

Nagpur: The Nagpur Municipal Corporation (NMC) has approved 12 private hospitals for the care of Covid-19 positive patients should there be a further rise in infection cases. Such hospitals can be brought into use by the civic body sometime after April 27.

On April 21 that municipal commissioner Tukaram Mundhe had ordered 13 private hospitals to be ready to treat Covid-19 positive patients.

In this regard, Mundhe released a notification on 23 April. The NMC plans to establish ready government and private hospitals with a total capacity of 5,000 beds. The room at IGGMCH and GMCH, in the current situation, is about 220 beds.

The civic chief told that after capacity at government hospitals is depleted, private hospitals will be placed into service as Covid-19 centers. “Be prepared for whatever situation needs to be,” he said.

The 12 hospitals on NMC’s list each have 100 beds or more. In addition, 29 more hospitals with a capacity of 50-100 beds have been identified and will be available for use in the event of 12 notified hospitals.

The NMC is also planning 7,000-bed institutional quarantine facilities, with 1,500 beds in the first phase. For 41 private hospitals dedicated to Covid-19 patients, the NMC also aims to alert several other private hospitals for other forms of diseases as non-Covid-19 centres.